From Ion-Channels to Porins: Engineering DNA-Based Synthetic Counterparts
نویسندگان
چکیده
منابع مشابه
Synthetic Ion Channels from Lipophilic Guanosine Derivatives
Title of Dissertation: SYNTHETIC ION CHANNELS FROM LIPOPHILIC GUANOSINE DERIVATIVES Ling Ma, Doctor of Philosophy, 2009 Dissertation directed by: Professor Jeffery T. Davis Department of Chemistry and Biochemistry Synthetic ion channels and pores not only represent models of natural transmembrane ion channels, but also demonstrate their potential applications in the areas of drug delivery, bios...
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In this perspective I tell the story (albeit a clearly abridged version) of how our knowledge of ion conduction through ion channels has evolved from a purely electrical concept to a structural dynamics view of ions interacting with a membrane protein. Our progress in this field has shown steady growth over the years but has also been interspersed with sudden jumps of discovery. These leaps hav...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2016
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2015.11.1889